METHOD FOR SIMULATING ACUTE PURULENT DESTRUCTIVE COXITIS IN LABORATORY ANIMALS Russian patent published in 2013 - IPC G09B23/28 

Abstract RU 2494468 C1

FIELD: medicine.

SUBSTANCE: simulating acute destructive purulent coxitis in laboratory animals is ensured by an open blood supply damage of a whirl bone by transection and ligation of a round ligament of the whirl bone. The ligation is preceded by hip joint infection by introducing a pathogenic culture of microorganisms into the vessels of the transected ligament. The destructive processes are stimulated by area-limited cartilage disintegration in the loaded areas in contact within the femoral bone and cotyloid cavity.

EFFECT: method provides the effective and fast-paced model of the disease with a low mortality of the laboratory animals.

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RU 2 494 468 C1

Authors

Dzjuba German Grigor'Evich

Erofeev Sergej Aleksandrovich

Chernigov Jurij Vladimirovich

Kondrakhin Igor' Sergeevich

Odarchenko Dmitrij Igorevich

Dates

2013-09-27Published

2012-03-05Filed