FIELD: chemistry.
SUBSTANCE: N-vinylpyrrolidone-based copolymer in form of pharmaceutically acceptable additive salts of acids is represented by general formula 
(I), where R stands for hydrogen or methyl; content of monomer units n constitutes 25-90 mol.%; X stands for anion of pharmaceutically acceptable inorganic or organic acid; k equals 1 or 2; m takes values from 0.1 to 1.0; and average-viscosity molecular weight of copolymer Mµ equals 15-150 kDa.
EFFECT: invention makes it possible to extend arsenal of biologically active copolymers, which have improved characteristics of solubility, and which demonstrate larger activity as immunostimulant, prolonger of antibiotics action, activator of IL-1 production and phagocytosis than known analogous compounds.
6 tbl, 11 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COPOLYMER CONTAINING N-VINYL PYRROLIDONE, 2-METHYL-5-VINYL PYRIDINE AND 4-VINYL PYRIDINE LINKS | 2011 |
|
RU2459838C1 |
| COPOLYMERS OF 4-VINYLPYRIDINE OR 2-METHYL-5-VINYLPYRIDINE AND N-VINYLPYRROLIDONE WITH TERMINAL CYANOVALERIC ACID RESIDUE AND USE THEREOF TO TREAT PNEUMOCONIOSIS | 2014 |
|
RU2550820C1 |
| COPOLYMERS OF 2-METHYL-5-VINYL-PYRIDINE AND N-VINYLPYRROLIDONE, ACTIVATING PRODUCTION OF INTERLEUKIN-1, AND USE THEREOF AS ANTI-CANCER AGENTS | 2010 |
|
RU2430932C1 |
| COPOLYMERS OF 2-METHYL-5-VINYL-PYRIDINE AND N-VINYL PYRROLIDONE, HAVING PHAGOCYTOSIS ACTIVATOR PROPERTIES | 2010 |
|
RU2430933C1 |
| OPHTHALMIC PREPARATION PRESENTED IN FORM OF EYE DROPS AND CONTAINING BRANCHED POLYHEXAMETHYLENE GUANIDINES AND POLY(N-VINYLPYRROLIDONE) | 2012 |
|
RU2509562C1 |
| INTERPOLYMER POLYELECTROLYTE COMPLEX AND A PROLONGED IMMUNOSTIMULATING AGENT ON ITS BASIS, FOR MEDICAL AND VETERINARY USE | 2017 |
|
RU2683947C1 |
| N-VINYLPYRROLIDONE BASED COPOLYMERS | 2010 |
|
RU2415876C1 |
| MEDICINAL AGENT BASED ON SYNTHETIC COPOLYMER OF VINYLPYRIDINE ROW FOR TREATING TISSUE HELMINTHIASIS | 2019 |
|
RU2727935C1 |
| IMPLANTED DRUG PREPARATION OF NALTREXONE FOR TREATING ALCOHOL- OR OPIOID-DEPENDENT PATIENTS | 2012 |
|
RU2476209C1 |
| IMPLANTABLE MEDICATION DISULFIRAM-BASED FOR TREATMENT OF ALCOHOL OR OPIATE-DEPENDENT PATIENT | 2012 |
|
RU2475272C1 |
