TOPICAL COMPOSITION Russian patent published in 2013 - IPC A61K31/196 A61K47/10 A61K47/00 A61K9/06 A61K9/08 A61K9/107 A61P29/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a topical pharmaceutical composition in the form of an opaque emulsion gel. The composition contains 1.2-4 wt % of diclofenac diethylammonium salt, saturated or unsaturated C₁₀-C₁₈fatty alcohol, at least 40 wt % of water, C₂-C₄alkanol, glycol solvent, gelling agent, liquid lipid forming an oil phase of the emulsion gel, non-ionic surfactant and agent with the primary properties to reduce pH of the prepared composition to 6-9.

EFFECT: compositions under the invention are characterised by high skin permeability, extremely low systemic absorption, absence of human skin irritation after application, high chemical and physical stability, complete solubility of the active component and considerable relief of pain intensity.

8 cl, 4 tbl, 5 ex