INTRAPULMONARY ADMINISTRATION OF FUOROQUINOLONE Russian patent published in 2013 - IPC A61K31/496 A61K9/14 A61K9/12 A61K9/72 A61P31/04 A61P11/00

Abstract RU 2497524 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: powder composition for intrapulmonary administration contains particles of ciprofloxacin betaine 3,5-hydrate and an excipient. The particles have a mass median aerodynamic diameter making from approximately 1 to approximately 5 mcm; a pulmonary half-life of betaine 3,5-hydrate makes min. 1.5 h; while a roughness of the composition falls within the range of 3 to 10.

EFFECT: composition may be used to treat an endobronchial infection, such as an infection caused by Pseudomonas aeruginosa, and it is most applicable for treating mucoviscidosis.

6 cl, 8 dwg, 16 tbl, 12 ex

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RU 2 497 524 C2

Authors

Virs Dzheffri

Tarara Tomas

Dates

2013-11-10—Published

2009-05-15—Filed