NEW DOSE AND FORMULATION Russian patent published in 2017 - IPC A61K31/46 A61K9/72 A61K9/14 A61P11/08 

Abstract RU 2608713 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to pharmaceutical composition for inhalation. Above composition contains as the only active ingredient aclidinium in form of dry powder mixed with pharmaceutically acceptable carrier in form of dry powder, where weight ratio of aclidinium and carrier makes from 1:25 to 1:75, and metered nominal dose of aclidinium is equivalent to 400 mcg (plus / minus 10 %) of aclidinium bromide. Invention also relates to methods of treating respiratory disorder specified from asthma and chronic obstructive pulmonary disease, which involve administering said composition and multi-dose inhalation device calibrated to facilitate introduction of measured nominal dose of aclidinium, equivalent to 400 mcg (plus / minus 10 %) of aclidinium bromide.

EFFECT: invention provides considerable and stable increase in forced expiratory volume per second in patients with COPD.

14 cl, 1 tbl, 1 ex

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RU 2 608 713 C2

Authors

Rosa Lamarka-Kasado

Gonsalo De-Mikel-Serra

Dates

2017-01-23Published

2009-03-13Filed