IMMUNOMODULATORY COMPOUNDS AND TREATING DISEASES CONNECTED WITH INFLAMMATORY CYTOKINES Russian patent published in 2013 - IPC A61K38/04 A61P37/02 

Abstract RU 2498813 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine, namely to using at least one immunomodulatory compound of general formula (1) or a pharmaceutically acceptable, solvate or isomer thereof for preparing a pharmaceutical composition for treating a disease or disorder specified in asthma, atopic dermatitis, allergic rhinitis, inflammatory intestinal disease, diabetes or rheumatoid arthritis in homoiothermal animal, including a human. What is also presented is using (5S,11R)-1-amino-5-[(R)-3-dodecanoyloxytetradecanoylamino]-6-oxo-7-aza-11-[(R)-3-hydroxytetradecanoylamino]dodecan-12-ol-12-dihydrophosphate (OM-294-BA-MP (S,R)) or a pharmaceutically acceptable salt, solvate or isomer thereof for preparing the pharmaceutical composition.

EFFECT: group of inventions provides treating the above diseases by modulating the TH1/TH2 cytokine balance by reducing TH2-cytokine release and enhancing TH2-cytokine production.

11 cl, 16 dwg, 14 ex

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RU 2 498 813 C2

Authors

Boer Zhak

K'Javaroli Karlo

Mutel' Stefan

Dates

2013-11-20Published

2007-03-09Filed