METHOD OF PRODUCING 3-TRIFLUOROMETHYL CHALCONES Russian patent published in 2013 - IPC C07C49/80 C07C49/813 C07C45/74 C07C45/68 C07C45/61 C07D261/04 C07C25/13 

FIELD: chemistry.

SUBSTANCE: invention relates to an improved method of producing a compound of formula , where Z is optionally substituted phenyl and Q is phenyl or 1-naphthalenyl, each optionally substituted. The method involves distillation of water from a mixture containing a compound of formula , a compound of formula , a base containing at least one compound selected from a group comprising alkali-earth metal hydroxides of formula 4 M(OH)₂, where M is Ca, Sr or Ba, alkali metal carbonates of formula 4a (M¹)₂CO₃ , where M¹ is Li, Na or K, 1,5-diazabicyclo[4,3.0]non-5-ene and 1,8-diazabicyclo[5.4.0]undec-7-ene, and an aprotic solvent capable of forming a low-boiling azeotrope with water. The invention also relates to a method of producing a compound of formula 2, a method of producing a compound of formula from a compound of formula 1 and a compound of formula 2.

EFFECT: method enables to obtain a product with high output.

20 cl, 15 tbl, 8 ex