PHARMACEUTICAL COMPOUND Russian patent published in 2020 - IPC C07D231/56 C07D401/04 C07D401/14 C07D403/04 C07D403/14 C07D405/04 C07D405/14 C07D413/04 C07D413/14 C07D417/12 C07D417/14 C07D471/04 C07D471/08 C07D471/10 C07D487/04 C07D487/10 C07D498/10 C07D513/04 A61K31/416 A61K31/438 A61K31/439 A61K31/4523 A61K31/454 A61K31/496 A61K31/4985 A61K31/499 A61K31/4995 A61K31/5377 A61K31/551 A61P9/10 A61P15/00 A61P25/04 A61P25/14 A61P25/16 A61P25/18 A61P25/28 A61P27/12 A61P29/00 A61P31/04 A61P31/12 A61P35/00 A61P35/02 

Abstract RU 2719446 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to specific compounds specified in claim 1, as well as to a compound having general formula given below, where R4 is selected from hydrogen, halogen and C1-C6 alkyl; and Y is a group having formula given below, where L is absent, each R313 is independently selected from H, halogen and C1-C6 alkyl and R" is selected from H and C1-C6 alkyl or its pharmaceutically acceptable salts. Declared compounds inhibit tryptophan-2,3-dioxygenase (TDO) or indolamine-2,3-dioxygenase (IDO). Invention also relates to pharmaceutical compositions based on said compounds. .

EFFECT: disclosed is a pharmaceutical compound.

6 cl, 2 dwg, 3 tbl, 2 ex

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RU 2 719 446 C2

Authors

Kiczun, Michael

Davis, Susan

Wise, Alan

Cowley, Phillip

Dates

2020-04-17Published

2015-11-02Filed