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2 507 596

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IPC

G09B23/28(2006-01-01)

A61K31/195(2006-01-01)

A61P43/00(2006-01-01)

(21) (22)

Application

2012157914/14, 2012-12-27

(24)

Start date

2012-12-27

(22)

Actual filing date

2012-12-27

(45)

Published

2014-02-20

(72)

Inventor

Pokrovskij Mikhail VladimirovichLazarenko Viktor Anatol'EvichKolesnik Inga MikhajlovnaPapuashvili Mikhail MerabovichTrofimov Konstantin SergeevichPokrovskaja Tat'Jana Grigor'EvnaDolzhikov Aleksandr Anatol'EvichKhodov Sergej VladimirovichGudyrev Oleg SergeevichKochkarov Vladimir Iskhakovich

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhranenija Rossijskoj Federatsii

METHOD FOR PHARMACOLOGICAL CORRECTION OF SKELETAL MUSCLE ISCHEMIA WITH L-NORVALINE Russian patent published in 2014 - IPC G09B23/28 A61K31/195 A61P43/00

Abstract RU 2507596 C1

FIELD: medicine.

SUBSTANCE: skeletal muscle ischemia in rats is corrected by simulating leg muscle ischemia on the second experimental day. The ischemia is corrected by the intragastric administration of L-norvaline in a daily dose of 10.0 mg/kg from the first experimental day every 46 hours for 7 experimental days.

EFFECT: effective experimental treatment of the skeletal muscle ischemia ensured by stimulation of neovasculogenesis.

1 ex, 1 tbl

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RU 2 507 596 C1

Authors

Pokrovskij Mikhail Vladimirovich

Lazarenko Viktor Anatol'Evich

Kolesnik Inga Mikhajlovna

Papuashvili Mikhail Merabovich

Trofimov Konstantin Sergeevich

Pokrovskaja Tat'Jana Grigor'Evna

Dolzhikov Aleksandr Anatol'Evich

Khodov Sergej Vladimirovich

Gudyrev Oleg Sergeevich

Kochkarov Vladimir Iskhakovich

Dates

2014-02-20—Published

2012-12-27—Filed