METHOD FOR STIMULATING NEOANGIOGENESIS IN ISCHEMIC SKELETAL MUSCLE Russian patent published in 2015 - IPC G09B23/28 A61K31/335 A61P9/10 

Abstract RU 2547692 C1

FIELD: medicine.

SUBSTANCE: shin muscle ischemia is simulated in laboratory animals on the second experimental day by surgical removal of a portion of great vessels, including femoral, popliteal, anterior and posterior tibial arteries. The ischemia is corrected by the intragastric administration of dihydroquercetin in a daily dose of 5.5 mg/kg every 46 hours of the first 7 experimental days.

EFFECT: effective treatment of the skeletal muscle ischemia by stimulating neoangiogenesis that is proved by laser Doppler flowmetry and morphological analysis.

1 ex

Similar patents RU2547692C1

Title Year Author Number
METHOD OF PHARMACOLOGICAL CORRECTION OF ISCHEMIA OF SKELETAL MUSCLE WITH RESVERATROL 2012
  • Pokrovskij Mikhail Vladimirovich
  • Lazarenko Viktor Anatol'Evich
  • Kolesnik Inga Mikhajlovna
  • Trofimov Konstantin Sergeevich
  • Pokrovskaja Tat'Jana Grigor'Evna
  • Dolzhikov Aleksandr Anatol'Evich
  • Khodov Sergej Vladimirovich
  • Gudyrev Oleg Sergeevich
  • Kochkarov Vladimir Iskhakovich
  • Stupakova Elena Gennad'Evna
RU2518965C1
METHOD FOR PHARMACOLOGICAL CORRECTION OF SKELETAL MUSCLE ISCHEMIA WITH L-NORVALINE 2012
  • Pokrovskij Mikhail Vladimirovich
  • Lazarenko Viktor Anatol'Evich
  • Kolesnik Inga Mikhajlovna
  • Papuashvili Mikhail Merabovich
  • Trofimov Konstantin Sergeevich
  • Pokrovskaja Tat'Jana Grigor'Evna
  • Dolzhikov Aleksandr Anatol'Evich
  • Khodov Sergej Vladimirovich
  • Gudyrev Oleg Sergeevich
  • Kochkarov Vladimir Iskhakovich
RU2507596C1
METHOD OF PHARMACOLOGICAL CORRECTION OF SCELETAL MUSCLE ISCHEMIA WITH SILNEDAFIL INCLUDING IN L-NAME INDUCED NITROGEN OXIDE DEFICIENCY 2012
  • Pokrovskij Mikhail Vladimirovich
  • Kolesnik Inga Mikhajlovna
  • Khodov Sergej Vladimirovich
  • Pokrovskaja Tat'Jana Grigor'Evna
  • Dolzhikov Aleksandr Anatol'Evich
  • Efremenkova Dar'Ja Afonas'Evna
  • Gudyrev Oleg Sergeevich
  • Molchanova Ol'Ga Viktorovna
  • Kochkarov Vladimir Iskhakovich
  • Zhernakova Nina Ivanovna
  • Dolzhikova Irina Nikolaevna
  • Danilenko Ljudmila Mikhajlovna
  • Bratchikov Oleg Ivanovich
  • Filimonov Vjacheslav Aleksandrovich
  • Arustamova Anna Aleksandrovna
  • Korokin Mikhail Viktorovich
  • Gureev Vladimir Vladimirovich
  • Korokina Lilija Viktorovna
  • Alekhin Sergej Aleksandrovich
  • Denisjuk Tat'Jana Alekseevna
RU2497203C2
METHOD FOR PHARMACOLOGICAL STIMULATION OF NEOANGIOGENESIS IN TREATING ACUTE EXPERIMENTAL LIMB ISCHEMIA 2014
  • Orlova Anzhelika Jur'Evna
  • Artjushkova Elena Borisovna
  • Sukovatykh Boris Semenovich
  • Gordov Maksim Jur'Evich
  • Abramova Svetlana Al'Bertovna
RU2559937C1
METHOD FOR PHARMACOLOGICAL CORRECTION OF EXPERIMENTAL CRITICAL SKELETAL MUSCLE ISCHEMIA WITH A COMBINATION OF SIMVASTATIN AND UDENAFIL 2020
  • Fejziev Elvin Ejnulla Ogly
  • Belous Aleksandr Sergeevich
  • Sukovatykh Boris Semenovich
  • Trubnikova Elena Vladimirovna
RU2727891C1
METHOD FOR SKELETAL MUSCLE EXPERIMENTAL ISCHEMIA PHARMACOLOGICAL CORRECTION USING TADALAFIL AND PENTOXIFYLLINE IN COMBINED THERAPY 2016
  • Lavrinenko Kristina Ivanovna
  • Belous Aleksandr Sergeevich
  • Mal Galina Sergeevna
  • Artyushkova Elena Borisovna
  • Polyakova Olga Vitalevna
  • Orlova Anzhelika Yurevna
  • Trubnikova Elena Vladimirovna
RU2618620C1
METHOD FOR SKELETAL MUSCLE EXPERIMENTAL ISCHEMIA PHARMACOLOGICAL CORRECTION USING SILDENAFIL AND PENTOXIFYLLINE IN COMBINED THERAPY 2016
  • Lavrinenko Kristina Ivanovna
  • Belous Aleksandr Sergeevich
  • Mal Galina Sergeevna
  • Artyushkova Elena Borisovna
  • Polyakova Olga Vitalevna
  • Orlova Anzhelika Yurevna
  • Trubnikova Elena Vladimirovna
RU2618621C1
METHOD FOR PHARMACOLOGICAL CORRECTION OF EXPERIMENTAL CRITICAL SKELETAL MUSCLE ISCHEMIA WITH SIMVASTATIN 2020
  • Fejziev Elvin Ejnulla Ogly
  • Belous Aleksandr Sergeevich
  • Sukovatykh Boris Semenovich
  • Trubnikova Elena Vladimirovna
RU2726076C1
METHOD FOR SKELETAL MUSCLE EXPERIMENTAL ISCHEMIA PHARMACOLOGICAL CORRECTION USING VARDENAFIL AND PENTOXIFYLLINE IN COMBINED THERAPY 2016
  • Lavrinenko Kristina Ivanovna
  • Belous Aleksandr Sergeevich
  • Mal Galina Sergeevna
  • Artyushkova Elena Borisovna
  • Polyakova Olga Vitalevna
  • Orlova Anzhelika Yurevna
  • Trubnikova Elena Vladimirovna
RU2618622C1
METHOD FOR PHARMACOLOGICAL CORRECTION OF EXPERIMENTAL CRITICAL SKELETAL MUSCLE ISCHEMIA WITH A COMBINATION OF SIMVASTATIN, UDENAFIL AND MONONUCLEAR FRACTION OF AUTOLOGOUS BONE MARROW 2020
  • Fejziev Elvin Ejnulla Ogly
  • Belous Aleksandr Sergeevich
  • Sukovatykh Boris Semenovich
  • Trubnikova Elena Vladimirovna
RU2726077C1

RU 2 547 692 C1

Authors

Kolesnik Inga Mikhajlovna

Pokrovskij Mikhail Vladimirovich

Lazarenko Viktor Anatol'Evich

Dates

2015-04-10Published

2014-02-13Filed