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2 727 891

(13)

(51)

IPC

G09B23/28(2006-01-01)

A61K31/351(2006-01-01)

A61K31/519(2006-01-01)

(21) (22)

Application

2020111675, 2020-03-20

(24)

Start date

2020-03-20

(22)

Actual filing date

2020-03-20

(45)

Published

2020-07-24

(72)

Inventor

Fejziev Elvin Ejnulla OglyBelous Aleksandr SergeevichSukovatykh Boris SemenovichTrubnikova Elena Vladimirovna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Universitet"

METHOD FOR PHARMACOLOGICAL CORRECTION OF EXPERIMENTAL CRITICAL SKELETAL MUSCLE ISCHEMIA WITH A COMBINATION OF SIMVASTATIN AND UDENAFIL Russian patent published in 2020 - IPC G09B23/28 A61K31/351 A61K31/519

Abstract RU 2727891 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to experimental pharmacology and surgery. Method of pharmacological correction of experimental ischemia of skeletal muscle with a combination of simvastatin and udenafil involves experimental modeling of critical ischemia of shin muscles, where simvastatin is administered intragastrically in dose of 0.86 mg/kg and udenafil is administered intragastrically in dose of 0.86 mg/kg once a day daily for 14 days.

EFFECT: invention can be used to simulate critical skeletal muscle ischemia.

1 cl, 1 tbl, 1 ex

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RU 2 727 891 C1

Authors

Fejziev Elvin Ejnulla Ogly

Belous Aleksandr Sergeevich

Sukovatykh Boris Semenovich

Trubnikova Elena Vladimirovna

Dates

2020-07-24—Published

2020-03-20—Filed