METHODS FOR PRESERVING RENAL FUNCTION WITH USING XANTHINE OXIDOREDUCTASE Russian patent published in 2014 - IPC A61K31/352 A61K31/382 A61K31/415 A61K31/425 A61P13/12 

Abstract RU 2508099 C2

FIELD: medicine.

SUBSTANCE: group of inventions refers to nephrology, and can be used for preserving the renal function in an individual in need thereof who suffers gout, acute gouty arthritis, chronic gouty arthropathy, chalky gout. That is ensured by administering an effective amount of 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazol-5-carboxyl acid or a pharmaceutically acceptable salt thereof. The renal function is elevated by at least one of blood serum creatinin, creatinin clearance and glomerular filtration rate, wherein the individual's glomerular filtration rate (GFR) is maintained at the level of approximately 75% or more as compared to an individual's initial glomerular filtration rate (GFR).

EFFECT: using the given inventions enables preserving the renal function.

2 cl, 6 dwg, 8 tbl, 3 ex

Similar patents RU2508099C2

Title Year Author Number
COMBINED USE OF COMPOUND A AND COMPOUND B FOR PRODUCTION OF DRUGS FOR TREATMENT OF GOUT OR HYPERURICEMIA 2019
  • Chen, Tszyanven
  • Shen, Yan
  • Nin, Zhuj
RU2783862C1
THERAPEUTIC OR PREVENTIVE AGENT FOR TUMOUR LYSIS SYNDROME 2013
  • Ueda Takanori
  • Yamauti Takakhiro
  • Morita Mikhoko
  • Khoriuti Khideki
RU2627591C2
METHODS AND COMPOSITIONS FOR TREATING HYPERURICEMIA AND METABOLIC DISORDERS ASSOCIATED WITH HYPERURICEMIA 2012
  • Ku Mannching Sherri
  • Chen Chikh-Kuang
  • Lu Vej-Shu
  • Lin I-In
RU2603050C2
MODIFIED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING FEBUXOSTAT 2011
  • Tanedzha Radzhneesh
  • Gupte Vidzhaj
  • Vakilinedzhad Madzhid
RU2602188C2
INTRACELLULAR ATP INCREASING COMBINATION 2016
  • Nishino, Takeshi
  • Kamatani, Naoyuki
RU2728722C2
USE OF DERIVATIVES CONTAINING THE C-O-P BONDS IN THE PATIENTS WITH RENAL INSUFFICIENCY 2014
  • Perello Bestard Joan
  • Salcedo Roca Carolina
  • Ferrer Reynes Miquel David
  • Isern Amengual Bernat
  • Joubert Pieter H.
RU2725626C2
CRYSTAL OF AZOLE BENZENE DERIVATIVE 2015
  • Kawana, Asahi
  • Miyazawa, Yuki
RU2675854C2
SODIUM SALT OF THE URIC ACID TRANSPORTER INHIBITOR AND ITS CRYSTALLINE FORM 2016
  • U Guajli
  • Tsyu Chzhentszyun
  • Su Yunpen
  • Lu Si
RU2719484C2
ALPORT SYNDROME TREATMENT OPTIONS 2018
  • Wright, Timothy
RU2791694C2
TETRAZOLE COMPOUNDS FOR REDUCING CONCENTRATION OF URIC ACID 2009
  • O'Nejl Dzhejms Dennen
  • Sharma Shalini
  • Arudchandran Ramachandran
RU2522458C2

RU 2 508 099 C2

Authors

Lademakher Kristofer

Makdonal'D Patrisija

Dates

2014-02-27Published

2007-11-13Filed