DETECTION METHOD OF PROTEINS IN AMYLOID STATE, AND SET FOR DETECTION OF PROTEINS IN AMYLOID STATE Russian patent published in 2014 - IPC C12P21/06 G01N33/48 G01N33/58 G01N33/84 C12Q1/00 

Abstract RU 2509155 C1

FIELD: biotechnologies.

SUBSTANCE: invention proposes a detection method of proteins in amyloid state, in which a specimen of lysate of yeast culture or tissue of a mammal is obtained, ionic detergent is added to the specimen, proteins are concentrated in an amyloid shape on a cellulose acetate membrane, and they are detected by means of aptomeres, their conjugates or antibodies specific to amyloid shape of proteins. Besides, a set for detection of proteins in amyloid state is proposed.

EFFECT: invention can be used in medicine for diagnostics of amyloid diseases.

9 cl, 6 dwg, 7 ex

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RU 2 509 155 C1

Authors

Mit'Kevich Ol'Ga Vladimirovna

Aleksandrov Aleksandr Ivanovich

Ter-Avanesjan Mikhail Davidovich

Dates

2014-03-10Published

2012-10-25Filed