METHOD OF TREATING OR PREVENTING DISEASE ASSOCIATED WITH DEPOSIT OF AMYLOID PROTEINS (VERSIONS) Russian patent published in 2014 - IPC A61K47/48 A61K39/385 A61P25/28 

FIELD: chemistry.

SUBSTANCE: invention relates to the field of biotechnology, namely to the application of a conjugate of an immunogenic peptide and can be used in medicine. The said conjugate, containing 1÷93 of immunogenic peptides Aβ(35-42) (SEQ ID NO: 2), or 1÷93 of immunogenic peptides Aβ(33-42) (SEQ ID NO: 3), or 1÷93 of immunogenic peptides Aβ(33-40) (SEQ ID NO: 4), connected with a native albumin by means of a linker region, containing cysteine and a bifunctional linker, on condition that the linker region is connected by means of cysteine to the N-end of not more than one immunogenic peptide, can be used for the application in treatment or prevention of a disease, associated with the deposit of amyloid proteins. The invention also relates to the application of a pharmaceutical composition, containing the said conjugate, for the treatment or prevention of the disease, associated with the deposit of the amyloid proteins.

EFFECT: invention makes it possible to efficiently reduce levels of the amyloid peptide with the application of a simple in obtaining structure of the immunogenic peptide conjugate.

9 cl, 8 dwg, 7 tbl, 3 ex