FIELD: medicine.
SUBSTANCE: group of inventions relate to medicine and deals with method of diagnosing neurodegenerative disease in individual, including the following stages (i) determination of one or several parameters, selected from group, consisting of 3ab40 or value of calculated parameter, selected from group, consisting of 2ab40+3ab40, 2ab40+3ab40+2ab42+3ab42 and 1ab40+2ab40+1ab42+2ab42; (ii) comparison of parameter value with standard value, corresponding to value of said parameter in standard sample; and (iii) diagnostics of neurodegenerative disease, in case if increase of parameter value in comparison with standard value is observed. Group of inventions also deals with method of detecting stage, preceding neurodegenerative disease, method of differentiating neurodegenerative disease from stage, preceding said neurodegenerative disease.
EFFECT: group of inventions provide high sensitivity and specificity of detection methods.
13 cl, 12 ex, 14 dwg, 12 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIBODY, SET AND METHOD OF DETERMINATION OF AMILOIDNY PEPTIDES | 2012 |
|
RU2571213C2 |
| PHYSIOLOGICALLY ACTIVE SUBSTANCE SRFM AS BLOOD BIOMARKER FOR DIAGNOSING HUMAN NEURODEGENERATIVE DISORDERS AND DISEASES | 2023 |
|
RU2822604C1 |
| HIGH-SENSITIVITY IMMUNOASSAYS AND KITS FOR DETECTING PEPTIDES AND PROTEINS OF INTEREST | 2007 |
|
RU2461837C2 |
| BIOMARKER AND METHODS FOR EARLY DIAGNOSIS OF ALZHEIMER'S DISEASE | 2015 |
|
RU2687272C2 |
| METHOD OF USE IN THERAPY | 2010 |
|
RU2579659C2 |
| METHOD OF DIAGNOSTICS OF NEURODEGENERATIVE DISEASES | 2011 |
|
RU2567665C2 |
| METHOD OF TREATING ALZHEIMER'S DISEASE | 2004 |
|
RU2385161C2 |
| METHODS AND COMPOSITIONS FOR TREATING AMYLOID DEPOSITS | 2013 |
|
RU2673484C2 |
| METHOD OF TREATING ALZHEIMER'S DISEASE | 2009 |
|
RU2526155C2 |
| METHOD OF DETERMINATION OF PREDISPOSITION TO ALZHEIMER'S DISEASE | 2003 |
|
RU2337142C2 |
