FIELD: biotechnologies.
SUBSTANCE: method involves enzymic hydrolysis of initial raw material, centrifugation with further sterilising filtration of the obtained substance through finely porous filters with pore diametre of 0.2 mcm. Donor blood erythromass is used as initial raw material, and first it is subject to hemolysis, virus inactivation, inactivation of a ferment after enzymic hydrolysis. Clarification is performed by means of hydrogen peroxide solution with final concentration of 0.83% with further exposure at 66°C during 15 minutes.
EFFECT: invention allows separating low-molecular peptides and increasing their biological activity.
2 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR EXTRACTING NATURAL ANTIMICROBIAL PEPTIDES FROM LEUKOCYTE-ERYTHROCYTE-PLATELET BLOOD MASS | 2019 |
|
RU2729016C1 |
| METHOD FOR FRACTIONATION OF LEUKOCYTE PROTEINS | 2019 |
|
RU2737730C2 |
| METHOD OF EXTRACTING LOW MOLECULAR PEPTIDES | 2008 |
|
RU2416243C2 |
| METHOD OF ISOLATING ENDOGENOUS ANTIMICROBIAL PEPTIDES FROM PLACENTAL TISSUE | 2022 |
|
RU2813979C2 |
| OPTIMIZED RELEASE OF ENDOGENOUS BETA-DEFENSINS | 2024 |
|
RU2825572C1 |
| METHOD OF OBTAINING FOOD ADDITIVES FROM SECONDARY FISH RAW MATERIALS USING HYDROLYSIS | 2018 |
|
RU2681352C1 |
| METHOD OF PRODUCING WHEY PROTEIN HYDROLYSATE WITH HIGH DEGREE OF HYDROLYSIS AND WHEY PROTEIN HYDROLYSATE WITH HIGH DEGREE OF HYDROLYSIS | 2010 |
|
RU2428047C1 |
| METHOD FOR OBTAINING DRUG WITH ANTI-COAGULANT ACTIVITY | 2020 |
|
RU2749424C1 |
| METHOD FOR PRODUCTION OF FOOD ADDITIVES FROM SECONDARY SMOKED FISH RAW MATERIAL WITH APPLICATION OF THERMAL HYDROLYSIS | 2020 |
|
RU2727904C1 |
| METHOD OF PRODUCING BIOPOLYMERS FROM HYDROLYSATES OF KERATIN-CONTAINING MATERIAL AND BIOPOLYMERS OBTAINED USING SAID METHOD | 2012 |
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RU2509093C1 |
