METHOD FOR EXTRACTING NATURAL ANTIMICROBIAL PEPTIDES FROM LEUKOCYTE-ERYTHROCYTE-PLATELET BLOOD MASS Russian patent published in 2020 - IPC C07K1/12 C12P21/06 G01N30/02 

Abstract RU 2729016 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology. Disclosed is a method of extracting natural antimicrobial peptides (AMP) from leukocyte-erythrocyte-platelet blood mass. Used is a leukocyte-erythrocyte-platelet blood mass pre-exposed to trypsin haemolysis. Separation of AMP is carried out by liquid chromatography on a separating column with three-fold use of Sephadex G-25.

EFFECT: invention enables to optimize the technology of extracting the most complete fraction of natural low-molecular weight peptides containing AMP, to use Sephadex G-25 several times after washing, regeneration and drying, to increase their biological value and to reduce the cost of production thereof.

1 cl, 2 tbl, 3 dwg

Similar patents RU2729016C1

Title Year Author Number
METHOD OF ISOLATING ENDOGENOUS ANTIMICROBIAL PEPTIDES FROM PLACENTAL TISSUE 2022
  • Bazikov Igor Aleksandrovich
  • Maltsev Aleksandr Nikolaevich
  • Efremenko Anna Aleksandrovna
  • Ramesh Kumar Gojyal
  • Amidzhakhan Nadzhirul Amin
  • Madkhu Gupta
RU2813979C2
OPTIMIZED RELEASE OF ENDOGENOUS BETA-DEFENSINS 2024
  • Igor Aleksandrovich Bazikov
  • Aleksandr Nikolaevich Maltsev
  • Anna Aleksandrovna Efremenko
  • Filipp Igorevich Bazikov
RU2825572C1
NIOSOMAL ANTIMICROBIAL GEL FOR TREATING DIABETIC ULCERS, WOUNDS, BURNS, INCLUDING THOSE INFECTED WITH ANTIBIOTIC-RESISTANT MICROORGANISMS 2021
  • Bazikov Igor Aleksandrovich
  • Maltsev Aleksandr Nikolaevich
  • Ramesh Kumar Gojyal
  • Amidzhakhan Nadzhirul Amin
  • Madkhu Gupta
RU2781402C2
METHOD FOR FRACTIONATION OF LEUKOCYTE PROTEINS 2019
  • Volkova Larisa Vladimirovna
  • Grishina Tatyana Alekseevna
  • Volkov Aleksandr Gennadevich
RU2737730C2
SEPARATION METHOD OF LOW-MOLECULAR PEPTIDES 2012
  • Volkova Larisa Vladimirovna
  • Kaz'Janin Aleksandr Viktorovich
  • Mal'Gina Dar'Ja Jur'Evna
RU2510398C2
METHOD OF PRODUCING BIOLOGICALLY ACTIVE PEPTIDE-AMINO ACID PREPARATION BASED ON HUMAN BLOOD PLASMA 2022
  • Platonov Igor Artemevich
  • Kuznetsov Sergei Ivanovich
  • Anikina Mariia Andreevna
  • Kudriashova Alisa Aleksandrovna
RU2799637C1
METHOD OF EXTRACTING LOW MOLECULAR PEPTIDES 2008
  • Ternovskaja Larisa Nikolaevna
  • Gapon Marina Nikolaevna
  • Vaserin Jurij Ivanovich
  • Beskrovnaja Julija Grigor'Evna
RU2416243C2
ANTIBACTERIAL AGENT AND PHARMACEUTICAL COMPOSITION COMPRISING EFFECTIVE AMOUNT OF ANTIBACTERIAL AGENT 2005
  • Ivanov Jurij Borisovich
  • Cherkasov Sergej Viktorovich
  • Bukharin Oleg Valer'Evich
RU2278675C1
METHOD FOR ANTIMICROBIAL PEPTIDE CECROPIN P1 PRODUCTION FROM PINNATED KALANCHOE TRANSGENIC PLANTS EXTRACT 2016
  • Zakharchenko Natalya Sergeevna
  • Buryanov Yaroslav Ivanovich
RU2632116C1
BACILLUS SUBTILIS STRAIN - PRODUCER OF A LOW-MOLECULAR ANTIMICROBIAL PEPTIDE AND METHOD FOR PRODUCING A LOW-MOLECULAR ANTIMICROBIAL PEPTIDE 2020
  • Dyatlov Ivan Alekseevich
  • Pokhilenko Viktor Danilovich
  • Perelygin Vladimir Vladimirovich
  • Dunajtsev Igor Anatolevich
  • Kalmantaev Timur Akhmerovich
  • Chukina Irina Anatolevna
  • Somov Aleksej Nikolaevich
  • Detushev Konstantin Vladimirovich
  • Bogun Aleksandr Gennadevich
RU2758060C1

RU 2 729 016 C1

Authors

Bazikov Igor Aleksandrovich

Maltsev Aleksandr Nikolaevich

Baturin Vladimir Aleksandrovich

Ramesh K. Goyal

A. Nadzhirul Amin

Efremenko Anna Aleksandrovna

Dates

2020-08-04Published

2019-10-29Filed