METHOD FOR ESTIMATING INDICATIONS FOR PRESCRIBING DRUG PREPARATIONS INCOMPATIBLE WITH ALCOHOL INGESTION Russian patent published in 2014 - IPC A61B5/476 A61B5/16 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and may be used to estimate the indications for prescribing drug preparations incompatible with alcohol ingestion, in addictology, psychiatry, as well as psychotherapy. There are performed electroencephalography and psychological testing: the first stage involves electroencephalography (EEG) in the patients diagnosed with alcohol dependence syndrome for the presence of short wave, desynchronosis and asymmetric bioelectric brain activity, disturbed alpha activity; the given study aims at finding the presence or absence of an organic pathology of brain functioning related to disturbed bioelectric activity. At the second stage, the patients with EEG findings showing no signs of an organic brain involvement are estimated considering the personal nonverbal emotional attitude system using colour repertory grid (CRG) techniques with using groups of alcohol-related objects and displaying Luscher colour cards. Pearson linear correlation coefficients of the elements and constructs to be further processed using a principal component analysis procedure. The detected factor loadings of the two most important components are used as two-dimensional element coordinates when constructing a graphical model of the attitude system of the person being tested. The presence of high conformity in the two representational personal emotional attitude system (verbal and nonverbal) gives evidence of the intact and adequate personality motivation sphere and serves as an indication for prescribing drug preparations of opioid receptor antagonists (naltrexone) and a cognitive behaviour therapy of alcohol dependency. The presence of low conformity is a sign of such disturbances of the motivation sphere that neutralise possibilities of psychotherapeutic methods and serves as a proof for prescribing drug preparations incompatible with alcohol ingestion (disulphiram, cyanamide).

EFFECT: method enables the objective and accurate estimation of the correctness of indications in predicting the effective use of drug preparations incompatible with alcohol ingestion, within the alcohol dependence therapy.

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