FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to field of microbiology and deals with method of obtaining RTX-toxin ApxI. Claimed method is realised by cultivation of bacteria Actinobacillus pleuropneumoniae in culture medium, which provides growth of bacteria, and said culture medium contains borogluconate in concentration lower than 60 mmol/l in order to form in medium calcium-bologluconate complex.
EFFECT: invention makes it possible to increase output of RTX-toxin ApxI, which can be applied in production of vaccines.
5 cl, 4 tbl
| Title |
Year |
Author |
Number |
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