FIELD: medicine.
SUBSTANCE: what is used is a targeted transport of antibacterial drugs to an area of inflammation by a single use of an extracorporeal antibiotic therapy including the antibiogram findings. With underlying intraoperative autologous blood donation combined with hypervolemic haemodilution and neuraxial anaesthesia, the infusion is followed by an autologous blood exfusion in a volume of 5-10 ml/kg of body weight with the total volume of the infusion dominating over the volume of the autologous blood exfusion by 130-140%, with the autologous blood reinfusion following a surgical haemostasis.
EFFECT: invention reduces the postoperative inflammatory complications in high-risk groups, enables reducing a therapeutic dose and a frequency of administration of a drug, eliminating or reducing the amount of transfused blood components, avoiding an adverse effect on a foetus presented in the form of the newborn's microflora change and the appearance of antibiotic-resistant forms of pathogens.
2 ex
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Authors
Dates
2014-05-27—Published
2013-01-10—Filed