FIELD: medicine.
SUBSTANCE: intraoesophageal pH monitoring and Holter monitoring are recorded daily. The heart rate variability is estimated in the aggregate with an analysis of a nocturnal heart rate trend. If finding more than 5 episodes of high heart rate dispersion coinciding with reflux episodes, or if a nocturnal structure comprises more than 50% of the episodes, the disturbed vegetative regulation of heart rhythm related to gastrooesophageal reflux disease is diagnosed.
EFFECT: technique enables diagnosing the extra-oesophageal manifestations of gastrooesophageal reflux disease at the early stage of the disease after the subjective manifestations have been observed.
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