METHOD OF COMPLEX TREATMENT OF GASTROESOPHAGEAL DISEASE IN PATIENTS WITH OPISTHORCHOSIS Russian patent published in 2011 - IPC A61K31/575 A61K35/413 A61P1/16 A61P1/04 

FIELD: medicine.

SUBSTANCE: invention relates to medicine and is intended for treatment of gastroesophageal reflux disease (GERD) in patients with chronic opisthorchosis. PH-monitoring of upper parts of GIT and dehelmintisation are carried out. Type of reflux is determined. Preparations of ursodeoxycholic acid (UDCA) are administered. In case of mixed type of GER with prevalence of acid component dose is 250 mg/day for 2 weeks. In case of mixed type of GER with prevalence of alkali component dose is 500 mg/day before going to bed for 4 weeks. In isolated alkali version dose is 10 mg/kg in two intakes: morning and evening. In case of t^gen _pH>7 from 16.54 to 27.6%; N_pH>7 from 27 to 31, and GER t^gen _pH>7 from 27.6 to 48.8%; N_pH>7 from 31 to 35 - for 4 weeks. In case of t^gen _pH>7 from 16.54 to 27.6%; N_pH>7 from 27 to 31, and GER t^gen _pH>7 from 27.6 to 48.8%; N_pH>7 from 31 to 35 and in case of GER t^gen _pH>7 from 48.8 to 74.4%, N_pH>7 from 36 to 42 - for 8 weeks. In case of t^gen _pH>7 from 48.8 to 74.4%; N_pH>7 from 36 to 42, and GER t^gen _pH>7 from 16.54 to 74.4%; N_pH>7 from 27 to 42 -for 12 weeks.

EFFECT: method makes it possible to reduce motor-tonic disturbances of biliary tract, reduce number of recurrences, enhance treatment efficiency.

4 cl, 5 ex