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(19)

RU

(11)

2 619 840

(13)

C1

(51)

IPC

A61K31/513(2006-01-01)

A61K31/426(2006-01-01)

A61K47/32(2006-01-01)

A61K47/34(2006-01-01)

A61K9/10(2006-01-01)

A61P31/18(2006-01-01)

(21) (22)

Application

2016137670, 2016-09-21

(24)

Start date

2016-09-21

(22)

Actual filing date

2016-09-21

(45)

Published

2017-05-18

(72)

Inventor

Khazanova Elena SergeevnaNogaj Sergej YurevichYakovlev Dmitrij Vladimirovich

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennostyu Farma"

PHARMACEUTICAL COMPOSITION FOR HIV INFECTION TREATMENT Russian patent published in 2017 - IPC A61K31/513 A61K31/426 A61K47/32 A61K47/34 A61K9/10 A61P31/18 

Abstract RU 2619840 C1

FIELD: pharmacology.

SUBSTANCE: pharmaceutical composition for HIV infection treatment includes lopinavir, ritonavir in an effective amount and a polymer. At that, the pharmaceutical composition is prepared by extrusion. The composition comprises a matrix polymer consisting of PEG 6000/vinylcaprolactam/vinyl acetate of 5 to 25% by weight of the pharmaceutical composition in combination with copovidone of 45 to 65% by weight of the pharmaceutical composition. The composition is extruded at a temperature of 105 to 145°C.

EFFECT: invention allows to expand the arsenal of drugs with enhanced pharmacokinetic properties.

9 cl, 3 dwg, 11 ex

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RU 2 619 840 C1

Authors

Khazanova Elena Sergeevna

Nogaj Sergej Yurevich

Yakovlev Dmitrij Vladimirovich

Dates

2017-05-18—Published

2016-09-21—Filed

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