FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions is based on detecting eNOS activity modulation mechanisms and refers to a method for screening for endothelial NO-synthase (eNOS) modulator expression, a diagnostic technique for a cardiovascular disease in an individual, using NEUR1 for identifying a drug for preventing and/or treating a disease related to eNOS dysfunction, particularly the cardiovascular disease, using NEUR1 for detecting a signal transmission component in eNOS expression and using NEUR1 for eNOS promoter activity regulation.
EFFECT: group of inventions is effective in treating and preventing the diseases related to eNOS dysfunction.
25 cl, 6 dwg, 7 tbl, 4 ex
| Title | Year | Author | Number | 
|---|---|---|---|
| NOVEL EUKARYOTIC CELLS AND METHODS FOR PREPARING THEREOF FOR RECOMBINANT EXPRESSION OF PRODUCT OF INTEREST | 2014 | 
 | RU2712507C2 | 
| APPLICATION OF PAK INHIBITOR FOR ARTHROPATHY TREATMENT | 2004 | 
 | RU2360696C2 | 
| ANTIBODIES AGAINST ANGPTL3/8 COMPLEX AND METHODS OF THEIR USE | 2019 | 
 | RU2799796C2 | 
| TREATMENT OF BRAIN DERIVED NEUROTROPHIC FACTOR (BDNF) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO BDNF | 2013 | 
 | RU2661104C2 | 
| CANCER TREATMENT USING CHIMERIC ANTIGEN-SPECIFIC RECEPTOR BASED ON HUMANISED ANTI-EGFRvIII ANTIBODY | 2014 | 
 | RU2708032C2 | 
| HUMANISED ANTI-CXCR4 ANTIBODIES FOR TREATING CANCER | 2011 | 
 | RU2595394C2 | 
| COMPOUNDS FOR REMYELINATION BLOCKADE TREATMENT IN DISEASES RELATED TO EXPRESSION OF HERV-W SHELL PROTEIN | 2013 | 
 | RU2636355C2 | 
| MONOCLONAL ANTIBODY TO IL-5RΑ | 2017 | 
 | RU2698048C2 | 
| NOVEL EUKARYOTIC CELLS AND METHODS FOR PREPARING THEM FOR RECOMBINANT EXPRESSION OF A PRODUCT OF INTEREST | 2014 | 
 | RU2720525C2 | 
| DETECTING PAX2 FOR DIAGNOSING BREAST CANCER | 2009 | 
 | RU2522485C2 | 
Authors
Dates
2014-06-27—Published
2009-11-27—Filed