METHODS AND APPLICATIONS INCLUDING HEME PROTEIN 1 Russian patent published in 2014 - IPC G01N33/68 

Abstract RU 2520748 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions is based on detecting eNOS activity modulation mechanisms and refers to a method for screening for endothelial NO-synthase (eNOS) modulator expression, a diagnostic technique for a cardiovascular disease in an individual, using NEUR1 for identifying a drug for preventing and/or treating a disease related to eNOS dysfunction, particularly the cardiovascular disease, using NEUR1 for detecting a signal transmission component in eNOS expression and using NEUR1 for eNOS promoter activity regulation.

EFFECT: group of inventions is effective in treating and preventing the diseases related to eNOS dysfunction.

25 cl, 6 dwg, 7 tbl, 4 ex

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RU 2 520 748 C2

Authors

Krug Aleksandra

Kruip Jokhen

Vol'Fart Paulus

Gassenkhuber Jokhann

Kheermajer Katrin

Shtrobel' Khartmut

Karst Natali

Ferr'E Aleksandra

Viskov Kristian

Dates

2014-06-27Published

2009-11-27Filed