MATRIX FOR CELL TRANSPLANTOLOGY Russian patent published in 2014 - IPC A61F2/02 A61L27/14 A61K41/00 A61K47/30 

FIELD: medicine.

SUBSTANCE: invention refers to cell transplantology and tissue engineering, and describes a matrix, a basic element of which is a flat plate made from a spatially cross-linked hydrophobic polymer containing hydrophilic groups and forming on the plate surface a layer of saturated hydrocarbons having a chain length of 8 to 16 carbon atoms and directed preferentially along the normal line to the plate surface. The spatially cross-linked polymer is formed on substrates by exposing a photopolimerisable composition containing oligourethane methacrylate, a methacrylate monomer having a chain length of 8 to 18 carbon atoms, 2,2-dimethoxy-2-phenylacetophenone and 2,4-ditertbutylorthquinone, to light at a wave length of 320-380 nm.

EFFECT: matrix has a good adhesive capacity; it is biocompatible and bioresorbable, preserves progenitor cells, promotes their differentiation and growth, and is mechanically strong.

5 cl, 1 tbl, 5 ex, 8 dwg