FIELD: chemistry.
SUBSTANCE: invention describes novel derivatives of condensed pyrazole-, imidazole-, oxazole- and triazole pyrimidines, structural formulae of which are disclosed in the claims, as well as pharmaceutical compositions containing said compounds, and methods of using said compounds to treat or prevent diseases or disorders associated with cannabinoid receptor 1 (CB1) activity.
EFFECT: improved properties of compounds.
33 cl, 448 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| AZOLOPYRIMIDINES AS CANNABINOID 1 RECEPTOR INHIBITORS | 2007 |
|
RU2424242C2 |
| COMPOUNDS AND COMPOSITIONS AS PEROXISOME PROLIFERATOR RECEPTOR MODULATORS | 2005 |
|
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| SUBSTITUTED PYRAZOLOPYRIMIDINES AS GLUCOCEREBROSIDASE ACTIVATORS | 2011 |
|
RU2603637C2 |
| COMPOUNDS AND COMPOSITIONS AS MODULATORS OF ACTIVATED RECEPTORS OF PEROXISOME PROLIFERATOR | 2005 |
|
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| INDAZOL DERIVATIVES AS CRF ANTAGONISTS | 2003 |
|
RU2341518C2 |
| SUBSTITUTED INDOLE MANNICH BASES | 2000 |
|
RU2265594C2 |
| HYDROXYLATED AND METHOXYLATED CYCLOPENTA[B]PYRIMIDINES AS PROTEIN KINASE INHIBITORS | 2007 |
|
RU2478632C2 |
| COMPOUNDS AND COMPOSITIONS AS ITPKb INHIBITORS | 2007 |
|
RU2425826C2 |
| CYCLOPENTA(D)PYRIMIDINES AS PROTEIN KINASE AKT INHIBITORS | 2007 |
|
RU2481336C2 |
| COMPOUNDS AND COMPOSITIONS AS PROTEINKINASE INHIBITORS | 2005 |
|
RU2406725C2 |
