FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to the field of biotechnology. The claimed invention relates to the field of modulation of enzymatic activity by application of interaction between a molecular chaperone Hsp70 and lysosomal phospholipid bis(monoacylglycero)phosphate (BMP). The invention can be used in medicine.
EFFECT: interaction of Hsp70-BMP modulates activity of lysosomal compartment enzymes, interacting with BMP, therefore the claimed invention represents means of reversing pathology of lysosomal storage diseases.
21 cl, 16 dwg, 2 tbl, 3 ex
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Authors
Dates
2014-07-10—Published
2009-06-26—Filed