APPLICATION YEAST STRAIN Komagataella pastoris AS RECIPIENT FOR CONSTRUCTION OF PRODUCERS OF TARGET PROTEIN Russian patent published in 2014 - IPC C12N1/16 C12N1/19 C12N15/09 C12P21/02 

Abstract RU 2522479 C1

FIELD: biotechnology.

SUBSTANCE: application of yeast strain Komagataella pastoris RNCIM Y-727 as the recipient to construction of producers of target protein is characterised, optionally comprising introduction of mutations into it, providing the use of auxotrophic selective markers.

EFFECT: solution can be applied in preparation of recombinant proteins without the use of methanol as inductor of gene expression.

8 dwg, 4 tbl, 10 ex

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RU 2 522 479 C1

Authors

Tjurin Oleg Vladimirovich

Kozlov Dmitrij Georgievich

Cheperegin Sergej Ehduardovich

Gubajdullin Irek Il'Jasovich

Efremov Boris Dmitrievich

Klebanov Fedor Alekseevich

Dates

2014-07-20Published

2013-02-12Filed