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2 787 584

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IPC

C12N1/19(2006-01-01)

C12N15/81(2006-01-01)

C12N9/24(2006-01-01)

(21) (22)

Application

2022127026, 2022-10-18

(24)

Start date

2022-10-18

(22)

Actual filing date

2022-10-18

(45)

Published

2023-01-11

(72)

Inventor

Tkachenko Artur AleksandrovichGordeeva Tatyana LeonidovnaSineokij Sergej PavlovichBorshchevskaya Larisa NikolaevnaFedaj Tatyana Dmitrievna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Issledovatelskij Tsentr Institut"

KOMAGATAELLA PHAFFII YEAST STRAIN WITH INACTIVE HIS4 GENE - RECIPIENT FOR THE CONSTRUCTION OF MARKER-FREE STRAINS PRODUCING HETEROLOGOUS PROTEINS Russian patent published in 2023 - IPC C12N1/19 C12N15/81 C12N9/24

Abstract RU 2787584 C1

FIELD: biochemistry.

SUBSTANCE: the Komagataella phaffii yeast strain TGBF7 RNCIM Y-5013 with the inactivated HIS4 gene is proposed.

EFFECT: efficient construction of marker-free Komagataella phaffii yeast strain for obtaining heterologous proteins.

1 cl, 2 tbl, 3 ex

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RU 2 787 584 C1

Authors

Tkachenko Artur Aleksandrovich

Gordeeva Tatyana Leonidovna

Sineokij Sergej Pavlovich

Borshchevskaya Larisa Nikolaevna

Fedaj Tatyana Dmitrievna

Dates

2023-01-11—Published

2022-10-18—Filed