COMPOSITION FOR CELL-REPLACEMENT THERAPY OF SOFT TISSUE DEFECTS Russian patent published in 2014 - IPC A61K35/50 C12N5/02 C12N5/71 C12N5/797 A61P43/00 A61K38/18 

Abstract RU 2522816 C1

FIELD: biotechnology.

SUBSTANCE: composition is proposed which comprises stem cells of human amniotic fluid with the phenotype CD73+/CD90+/CD105+/CK19+, nutrient medium, erythropoietin, epidermal growth factor, and collagen taken in an effective amount.

EFFECT: invention enables to increase the proliferative potential and viability of the cells, while simultaneously providing cytoprotective effect on the cells of the transplant and stimulation of migration and proliferation of patient's own cells, and also to reduce significantly the concentration of injectable cells and to activate vascularisation and regeneration at the defect site and can be used in therapy for elimination of congenital and acquired defects of soft tissue arising as the result of injuries, after removal of tumors, congenital diseases, age-related changes or other damages.

2 tbl, 4 ex

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Authors

Terskikh Vasilij Vasil'Evich

Vasil'Ev Andrej Valentinovich

Voroteljak Ekaterina Andreevna

Rippa Aleksandra Leonidovna

Davydova Dar'Ja Aleksandrovna

Kalinkina Marina Alekseevna

Dates

2014-07-20Published

2013-02-12Filed