METHOD FOR TREATING FROSTBITE USING MESENCHYMAL STEM CELLS ISOLATED FROM RED BONE MARROW Russian patent published in 2021 - IPC A61K35/28 A61P17/02 

FIELD: medicine.

SUBSTANCE: invention relates to medicine. Method for treating frostbite using mesenchymal stem cells isolated from red bone marrow and grown under hypoxic conditions consists in the fact that the surrounding healthy tissues in the damaged area are infiltrated with mesenchymal stem cells at the stage of acute inflammation, while cells that have passed no more than 4 passages in total or not more than 2 from the moment of thawing, while using mesenchymal stem cells, in the cell population of which the proportion of CD90, CD105, CD73 and CD29-positive cells exceeds 90%, and the proportion of CD11b, CD14, CD45 and CD34-positive cells does not exceed 5%, in addition, mesenchymal stem cells are used, capable of differentiation in osteogenic, chondrogenic and adipogenic directions.

EFFECT: invention provides growth stimulation and cell regeneration for treatment of frostbite and burns.

1 cl, 9 dwg, 2 tbl