METHOD OF OBTAINING SECONDARY AMINES Russian patent published in 2014 - IPC C07C209/52 C07C211/45 B82Y99/00 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of obtaining secondary amines, in particular to a novel method of imine hydration, which makes it possible to obtain secondary amines of the general formula where R₁=C₆H₅: R₂=_cyclo-C₆H₁₁, _cyclo-C₅H₉, -CH₂C₆H₅, (CH₃)₂CHCH₂(CH₃)CH-; R₁=-CH₂C₆H₅: R₂=_cyclo-C₆H₁₁, R₁= -C₆H₄OCH₃: R₂=_cyclo-C₅H_9. Compounds are widely applied in the organic synthesis as semi-products. The method lies in hydration of imines by gaseous hydrogen in the presence of a catalyst. As imines, used are benzalaniline, benzalcyclohexylimine, cyclohexylidene phenylimine, 4-methylpent-2-ylidene phenylimine, cyclopentylidene-4-methoxyphenylimine, cyclopentylidene phenylimine, and as the catalyst, used are nickel nanoparticles, obtained in situ by reduction of nickel (II) chloride with sodium borohydride in a ratio 1:2, respectively. The process is carried out under atmospheric pressure of hydrogen in a medium of isopropanol or tert-butanol at a temperature of 60-70°C for 8-12 hours.

EFFECT: simplification of the method of obtaining compounds of the claimed structural formula.

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