STABILISED COMPOSITION CONTAINING AT LEAST ONE ADRENERGIC COMPOUND Russian patent published in 2014 - IPC A61K9/00 A61K31/137 A61K47/02 

Abstract RU 2527680 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to the pharmaceutical industry and represents a liquid pharmaceutical composition for improving at least one medical condition requiring administration of an adrenergic compound into an individual; the pharmaceutical composition contains the adrenergic compound, wherein the adrenergic compound is epinephrine or its physiologically acceptable salt, and at least one antioxidant specified in a group consisting of bisulphite, metabisulphite and sulphite compounds, wherein a molar ratio of the adrenergic compound to at least one antioxidant measured as a sulphite equivalent falls within the range of 0.70-1.30 and wherein the pH value of the above liquid composition falls within the range of 2.0-5.0.

EFFECT: invention provides higher storage stability with substantially reduced sensitivity to induced light, thermal and oxidative degradation.

17 cl, 9 dwg, 3 ex

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RU 2 527 680 C2

Authors

Behjlli Alan Dzh.

Makdonal'D Kennet

Porteus Pamela

Khendri Sajmon

Dates

2014-09-10Published

2010-06-03Filed