METHOD FOR AUTHENTICATION AND DETERMINATION OF QUANTITATIVE CONTENT OF BENZETHONIUM CHLORIDE IN MEDICINAL DRUGS Russian patent published in 2014 - IPC G01N33/15 A61K31/14 

Abstract RU 2529814 C1

FIELD: chemistry.

SUBSTANCE: invention relates to medicinal drug quality control and provides a method of authenticating and determining the quantitative content of benzethonium chloride in medicinal drugs, which includes separating components of the drug via high-performance liquid chromatography, where the eluent used is a mixture of acetonitrile, tetrabutylammonium hydrophosphate, disubstituted potassium phosphate and water, with content of tetrabutylammonium hydrophosphate of 2.5 mM, content of disubstituted potassium phosphate of 5 mM, wherein separation of the components of the drug is carried out with column length of 125 mm.

EFFECT: high accuracy and faster analysis since there is no need for special sample preparation.

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RU 2 529 814 C1

Authors

Osipov Aleksej Sergeevich

Nechaeva Ekaterina Borisovna

Dates

2014-09-27Published

2013-05-20Filed