FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions relates to biotechnology. Claimed is a method of enriching probiotic microorganisms, selected from yeasts and bacteria, with organic selenium. A microorganism is cultivated in a medium, containing a compound of general formula or its salt, a stereoisomer or a mixture of stereoisomers in any ratio or its ether derivative. Also claimed are probiotic bacteria, enriched with organic selenium, with the content of organic selenium more than 50 mcgSe/g by dry weight, with the content of selenomethionine constituting more than 50% of the total content of selenium in the bacterium. Also claimed is application of enriched by the said way probiotic bacteria in a cosmetic, pharmaceutical or food product.
EFFECT: invention provides enrichment of probiotic microorganisms with non-toxic organic selenium with an increased output.
12 cl, 6 dwg, 4 tbl, 4 ex
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Authors
Dates
2014-10-10—Published
2009-08-28—Filed