OPHTHALMIC OINTMENT FORMULATION AND METHOD FOR PREPARING SAME Russian patent published in 2014 - IPC A61K9/06 A61K31/47 A61K47/06 A61P31/04 A61P27/02 

FIELD: pharmacology.

SUBSTANCE: as an antibacterial quinolone compound, a composition contains one of the quinolone compounds, namely lomefloxacin, or norfloxacin, or pefloxacin, or levofloxacin, or sparfloxacine, or moxifloxacin, or gatifloxacin, or gemifloxacin, or their acceptable salts; a preserving agent is paraben esters, or a mixture thereof, or benzalkonium chloride, or cetrimide, or chlorobutanol, or chlorhexidine, and an ointment base in the following proportions, wt %: quinolone compound - 0.05-0.9, preserving agents - 0.0,2, ointment base up to 100. Methods for preparing the composition provide the ointment homogeneity and stability.

EFFECT: group of inventions provides prolonging the period of therapeutic action of the ointment, reducing the dosage frequency.

6 cl, 6 tbl, 32 ex