METHOD FOR LABORATORY ASSESSMENT OF VAGINAL MUCOSA HEALTH IN RADIATION THERAPY OF MALIGNANT NEW GROWTHS WITH UNDERLYING ACCOMPANYING THERAPY Russian patent published in 2014 - IPC G01N33/48 C12Q1/06 

Abstract RU 2533240 C1

FIELD: medicine.

SUBSTANCE: method involves assessing radioreaction of the vaginal mucosa by visual examination, as well as assessing the vaginal epithelial condition by lactic acid bacilli testing and measuring by bacterioscopical and bacteriological analyses, performing the cytological examination of the surface and intermediate squamose epitheliocytes of the vaginal discharge followed by measuring and finding atrophic and dyskeratotic damages of the above cells. The laboratory examinations precede the radiation exposure and are repeated with the total basic dose (TBD) 20 Gy, 40 Gy and 60 Gy and 1 month after the completion of treatment.

EFFECT: invention is characterised by accessibility and low cost of production, and can be used in clinical practice for the purpose of the objective assessment of the vaginal mucosa health in radiation therapy of malignant new growths, particularly for the assessment of the early radiation reactions and injuries of the vaginal mucosa formed in the course of the therapy or in 3 near months thereafter, for the purpose of prediction of the developing radiation complications in the vagina, and if needed, the correction of the radiation exposure regimen, for the purpose of the radiation therapy compliance.

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RU 2 533 240 C1

Authors

Bojko Anna Vladimirovna

Erastova Elena Ivanovna

Dubovetskaja Oksana Borisovna

Mel'Nikova Vera Jur'Evna

Demidova Ljudmila Vladimirovna

Dunaeva Elena Anatol'Evna

Dates

2014-11-20Published

2013-04-18Filed