METHOD OF CHOOSING TACTICS OF MANAGING PATIENTS WITH CERVICAL NEOPLASIA Russian patent published in 2013 - IPC A61B1/02 A61B1/07 A61B1/303 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, gynecology and includes medical history taking, clinical examination, cytological test, extended colposcopy, bacterioscopic and bacteriological tests, test for sexually transmitted infections. Under colposcopy control carried out is high-speed optical coherence tomography (hOCT), with analysis of kinematic characteristics of cervical tissue, treated with 3% acetic acid: intensity, uniformity, variability, elasticity of vessels, mobility of integral image, presence and character of movement of subepithelial structures. On the basis of obtained data type of cervical tissue changes is determined. Scanning is carried out by smooth movement of OCT-device probe on entire surface of uterus (U) from cervical canal to periphery on 12 vectors of 12-hour conventional clock face in clockwise direction, starting from 12 o'clock, marking boundaries of U mucosa changes on each of them - transitions between image types: malignant, questionable, benign. Boundaries of pathological nidus are determined by application of cervical ruler, consisting of two metal plates or rods, located at 90° angle to each other, one is being shorter than the other, with applied points. Long plate is fixed in cervical canal, rotating it in clockwise direction under colposcopy control, nidus size is marked in mm on short plate scale, on 4 quadrants in accordance with conventional clock face. After that, U is treated with 2% aqueous Lugol solution and hOCT is carried out again on 12, 3, 6, 9 o'clock of conventional clock face, with control of boundaries, obtained by means of hOCT and iodine-negative sites. By means of cervical ruler size and shape of neoplasia are fixed to plan area of irradiation or excision trajectory, place for sampling of cytological material is determined. If images correspond to benign changes, photodynamic therapy is administered, in case of questionable or malignant changes - excision: electroconisation or radiowave resection on trajectory, marked during hOCT.

EFFECT: methods ensures objectivity and accuracy of selection of tactics for managing patients with U neoplasia, reduction of treatment terms, reduction of manipulation trauma.

3 cl, 2 ex