FIELD: medicine.
SUBSTANCE: implementing the method involves determining the content of biomarkers - matrix metalloproteinase 2 (MMP 2) and tissue inhibitor of metalloproteinase 1 (TIMP 1) in the patient's oral fluid sampled before or not earlier than 30 minutes following meals. Using the derived values enables diagnosing papilloma or cancer of patient's oral floor mucosa. Using the invention provides achieving a considerably higher accuracy of the differential diagnosis of benign and malignant new growths of the patient's oral floor mucosa on the day of vising, a considerably higher sensitivity of the differential instant diagnosis, a higher probability of detecting the processes of benign and malignant new growths in the patient's body both at the early stages of the disease, and at the later ones, as well as a considerably simpler preparation of the patient within certain time frames for sampling and storing the diagnostic material.
EFFECT: lower loss of sensitivity of the detection channel in the presence of multiple non-synchronous pulse noise and mutual interference.
3 cl, 5 ex
