FIELD: chemistry.
SUBSTANCE: invention relates to biochemistry and provides a pharmaceutical composition for treating Gaucher's disease, which contains as an active ingredient lyophilised plant cells which express recombinant human glucocerebrosidase, a pharmaceutically acceptable carrier, where said pharmaceutical composition is intended for oral administration and where said human glucocerebrosidase has high-mannose glycosylation.
EFFECT: invention enables to obtain an effective pharmaceutical composition for treating Gaucher's disease with high enzyme biological activity owing to high-mannose glycosylation thereof.
16 cl, 21 dwg, 3 tbl, 6 ex
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Authors
Dates
2014-12-10—Published
2009-12-23—Filed