FIELD: medicine.
SUBSTANCE: polymerase chain reaction method is used to recognise polymorphous variants of IL6 and TGFb1 genes. Recognising the homozygous genotype CC in -174 position of IL6 gene in males and females, as well as the heterozygous genotype GC in -915 position of TGFb1 gene in females enables predicting the high risk of the complicated clinical course of the urogenital Chlamydial infection.
EFFECT: invention enables deciding on reasonable grounds on selecting a therapeutic approach to a specific patient suffering from urogenital Chlamydial infection in order to prevent complications of the urogenital Chlamydial infection and reproductive dysfunctions.
4 tbl, 5 ex
Title | Year | Author | Number |
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METHOD OF PREDICTION OF IDIOPATHIC MALE INFERTILITY BASED ON ANALYSIS OF NUCLEOTIDE VARIANTS IN MITOCHONDRIAL CYTOCHROME B GENE | 2022 |
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RU2800406C1 |
METHOD OF DIFFERENTIALLY DIAGNOSING COMPLICATIONS IN MEN SUFFERING FROM UROGENITAL CHLAMIDIOSIS | 2005 |
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RU2307352C2 |
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RU2348424C2 |
CHLAMYDIA DIAGNOSIS METHOD | 2017 |
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RU2662940C1 |
METHOD FOR MATCHING IMMUNOCORRECTOR AND PREDICTING EFFICIENCY OF IMMUNOTHERAPY AT UROGENITAL INFECTIONS | 2001 |
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RU2216739C2 |
NANOANTIBODIES BINDING CHLAMYDIA TRACHOMATIS ANTIGEN, METHOD OF INHIBITING INFECTION CAUSED BY CHLAMYDIA TRACHOMATIS | 2012 |
|
RU2487724C1 |
METHOD OF TREATMENT OF COMPLICATED UROGENITAL CLAMIDIOSIS | 2007 |
|
RU2361595C1 |
METHOD FOR ASSESSING MUCOSAL IMMUNITY STATE OF OPEN CAVITIES OF DIFFERENT LOCALISATION ACCOMPANYING PREDICTION OF CLINICAL COURSE OF INFECTIOUS-INFLAMMATORY PROCESSES, AND METHOD FOR CORRECTING INFECTIOUS-INFLAMMATORY PROCESSES | 2014 |
|
RU2556958C1 |
REAGENT KIT FOR CHLAMYDIA TRACHOMATIS DNA DETECTION AND ITS APPLICATION | 2014 |
|
RU2621863C2 |
DIAGNOSTIC TECHNIQUE FOR PAPILLOMA VIRUS INFECTION | 2008 |
|
RU2379690C1 |
Authors
Dates
2014-12-20—Published
2012-09-28—Filed