METHOD FOR COMBINED PROCESSING OF SCLERAL BED FOLLOWING ENDORESECTION OF INTRAOCULAR NEW GROWTH Russian patent published in 2014 - IPC A61F9/08 A61N1/18 A61K31/409 A61P27/02 A61P41/00 

FIELD: medicine.

SUBSTANCE: endoresection of an intraocular new growth is followed by covering the scleral bed surface with a photosensitising gel (PS gel) containing 0.1% monoethylene diamine monoamide chlorine adipate e6. The PS gel exposure makes 3 minutes. The residual gel is taken off. An active portion of one needle electrode is intraocularly applied on the scleral bed in parallel with the retinotomy border at 0.5-0.7 mm. The second electrode is applied in parallel to the first one at 3-4 mm to the centre of the scleral bed. That is followed by performing an electrochemical lysis (ECL) at the current intensity of 5 mA for 10 seconds. The electrodes are gradually moved along the scleral bed surface first circle-wise, in parallel to the retinotomy border, then from the periphery to the centre. The ECL covers the entire area of the scleral bed at the current intensity of 5 mA for 10-15 seconds in each position of the electrodes. That is followed by intraocular photodynamic therapy (PDT) along the entire area of the scleral bed with involving the 1.5 mm surrounding tissues. The patient is exposed to laser light at a wave length of 662 nm, power density of 60 J/cm², by fields of 4 mm in diameter, circle-wise from the periphery to the centre, and involving the adjoining fields by 5% of the area.

EFFECT: avoiding the tumour cells remained viable on the scleral bed after the endoresection of the intraocular new growth, eliminating recurrences of tumours and metastases in the remote postoperative period.

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