METHOD OF PHOTODYNAMIC THERAPY OF INTRAOCULAR NEOPLASMS Russian patent published in 2012 - IPC A61N5/67 A61K31/409 A61P35/00 

Abstract RU 2467777 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and can be used for photodynamic therapy of intraocular neoplasms. For this purpose photosensitiser chlorine e6 monoethylene diamine monoamide adipinate is introduced intravenously in dose 0.4 mg/kg during 10 minutes. 60 minutes after finishing intravenous introduction of PS, fluorescent diagnostics of PS accumulation in neoplasm is started. Intensity of PS fluorescence in intraocular neoplasm is controlled. When maximal fluorescence of neoplasm in comparison with surrounding tissue is achieved, neoplasm is irradiated transpupillarily with laser radiation. Wavelength corresponds to maximum of luminous radiation absorption by photosensitiser.

EFFECT: method makes it possible to perform treatment of intraocular neoplasms of small and medium size, reduce dose of introduced preparation and density of laser radiation energy, accelerate complete tumour regress due to higher PS tropism by tumour cells.

3 cl, 3 dwg, 2 ex

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RU 2 467 777 C1

Authors

Belyj Jurij Aleksandrovich

Tereshchenko Aleksandr Vladimirovich

Ponomarev Gelij Vasil'Evich

Dates

2012-11-27Published

2011-07-26Filed