FIELD: chemistry.
SUBSTANCE: invention provides benzylidene furanone derivatives of (+)-usnic acid of formula 6-13 
as anti-tumour agents. The compounds exhibit cytotoxic activity with respect to tumour cell lines CEM-13, U-937, MT-4.
EFFECT: high activity.
2 dwg, 3 tbl, 8 ex
| Title | Year | Author | Number |
|---|---|---|---|
| LABDANE-TYPE 6-HYDROXYNAPHTHOQUINONES, HAVING CYTOTOXIC ACTIVITY ON HUMAN TUMOUR CELLS | 2012 |
|
RU2479582C1 |
| 4-ISOPROPYL-7-METHOXY-2A-METHYL-2,2A,2A,3,5A,9B-HEXAHYDROFLUORENE[9,1-BC]FURAN-8-OL, HAVING ANTITUMOR ACTIVITY | 2013 |
|
RU2535926C1 |
| FURILIDENE FURANONE DERIVATIVES OF USNIC ACID AS NEW ANTITUBERCULOSIS AGENTS | 2013 |
|
RU2533707C1 |
| DRUG WITH ANTI-INFLAMMATORY ACTIVITY | 2016 |
|
RU2617123C1 |
| N-ETHYLPIPERAZYLAMIDE OF BETULINIC ACID AS TRITERPENIC ANTITUMOUR AGENT | 2010 |
|
RU2445317C1 |
| 16-(1,2,4-OXADIAZOL-3-YL)-15,16-EPOXILABDANOIDS POSSESSING CYTOTOXIC ACTIVITY ON HUMAN TUMOUR CELLS | 2011 |
|
RU2473550C1 |
| N-[3-OXOLUP-20(29)-ENE-28-OIL]-2,2,6,6-TETRAMETHYLPIPERIDINE-4-YLAMINE WITH CYTOTOXIC ACTIVITY IN RESPECT OF HUMAN TUMOUR CELLS | 2017 |
|
RU2641900C1 |
| HYDROGENATED BETULONIC ACID AND AMIDES THEREOF AS TRITERPENE ANTI-TUMOUR AGENTS | 2010 |
|
RU2448115C1 |
| N,N'((ALKANDIYL)BIS[LABDA-7(9),13,14-TRIENE-4-CARBOXAMIDES] WITH ANTITUMOUR ACTIVITY | 2017 |
|
RU2654201C1 |
| 7-TRIAZOLYL-SUBSTITUTED HYDROXYSPYROSTANES WITH CYTOTOXIC ACTIVITY AGAINST HUMAN TUMOR CELLS | 2023 |
|
RU2798105C1 |
