FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to micheliolide derivatives of formula 
, a based pharmaceutical composition and using them for treating cancer. In formula (I) R1 represents H, -C(O)R4, wherein R4 represents C1-8alkyl; R2=R3 represents a double bond, or R3 represents H, and R2 represents substituted alkyl having from 1 to 8 carbon atoms, wherein a substitute represents -NR7R8; or its pharmaceutically acceptable salts; and wherein R7 and R8 can be identical or different, and represent C1-8alkyl; X represents oxygen; Y represents a single bond.
EFFECT: preparing the pharmaceutical composition for treating cancer.
6 cl, 1 tbl, 8 ex
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