FIELD: chemistry.
SUBSTANCE: method includes steps of: (1) extracting fermentation broth containing a compound of formula I or a salt thereof to obtain an extract 1 after filtering and centrifuging; (2) diluting or concentrating the extract 1 in a vacuum with reduction of organic solvent content to obtain an extract 2; (3) feeding the extract 2 into a macroporous adsorption resin; (4) washing the macroporous adsorption resin with water or a mixture of water and an organic solvent as a washing solution and (5) eluting the compound of formula I from the macroporous adsorption resin with the mixture of water and organic solvent as an eluent.
EFFECT: method enables to use a smaller amount of organic solvent and improves purity of the collected compound of formula I.
8 cl, 2 dwg, 2 tbl, 8 ex
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