CYCLIC (AZA)INDOLYSINCARBOXAMIDES, PREPARING AND USING THEM AS PHARMACEUTICAL AGENTS Russian patent published in 2015 - IPC C07D471/04 C07D487/04 A61K31/437 A61P9/12 

Abstract RU 2539574 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new cyclic indolysincarboxamides and azaindolysincarboxamides of formulas Ia and Ib:

presented below, wherein the values of R, Ra, R10, R20, R30, R40, Y, n, p and q are specified in cl. 1 of formula. What is described is a method for preparing them.

EFFECT: compounds exhibit rennin-inhibitory activity that enables using them in the pharmaceutical composition and for treating hypertension.

11 cl, 4 tbl, 17 ex

Similar patents RU2539574C2

Title Year Author Number
FUSED PYRROLEDICARBOXAMIDES AND THEIR USE AS PHARMACEUTICALS 2013
  • Biali Loran
  • Lorents Katrin
  • Virt Klaus
  • Shtajnmejer Klaus
  • Khessler Gerkhard
RU2650111C2
DERIVATIVES OF TETRAHYDROISOQUINOLINE, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF, METHOD FOR INHIBITION OF SYNAPTIC UPTAKE OF DOPAMINE AND TREATMENT METHOD 2000
  • Bek Dzhejms P.
  • Smit Mark A.
RU2293728C2
(HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS 2012
  • Ortega-Munos Alberto
  • Fajf Mattyu Kolin Tor
  • Martinel-Pedemonte Mark
  • Estyarte-Martines Mariya-De-Los-Ankheles
  • Vals-Vidal Nuriya
  • Kurs Guido
  • Kastro-Palomino-Lariya Khulio-Sesar
RU2668952C2
SUBSTITUTED CHROMAN-6-YLOXY-CYCLOALKANES AND USE THEREOF AS MEDICAMENTS 2014
  • Chekhtitskij Verngard
  • Ueston Dzhon
  • Rakelmann Nils
  • Kraft Folker
  • Arndt Petra
  • Virt Klaus
  • Gegelyajn Khajnts
  • Rittseler Olaf
RU2666350C2
AMINO-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND USE THEREOF AS PHARMACEUTICAL AGENTS 2012
  • Ruf Sven
  • Sadovski Torsten
  • Khorstik Georg
  • Shrojder Kherman
  • Buning Kristian
  • Olpp Tomas
  • Virt Klaus
RU2605600C2
SUBSTITUTED DERIVATIVES OF 3-THIAZOLAMINEPROPIONIC ACID AND THEIR USE AS PHARMACEUTICALS 2012
  • Ruf Sven
  • Pernershtorfer Jozef
  • Sadovski Torsten
  • Khorstik Georg
  • Shrojder German
  • Buning Kristian
  • Virt Klaus
RU2617843C2
CYCLIC AZAINDOLE-3-CARBOXAMIDE, PRODUCTION AND USE THEREOF AS THERAPEUTIC PREPARATIONS 2009
  • Shtajnkhagen Khenning
  • Shajper Bodo
  • Matter Khans
  • Makkort Gari
RU2487874C2
PYRAZOLOPYRIDINE DERIVATIVES AS KINASE INHIBITORS 2015
  • Ford Daniel Dzhejms
  • Ryuberson Dzhejms Tomas
RU2733400C2
BENZO[1,3]DIOXIN DERIVATIVES AND THEIR USE AS LPAR5 ANTAGONISTS 2013
  • Nazare Mark
  • Kotsian Detlef
  • Bossart Martin
  • Chekhtizkij Verngard
  • Efers Andreas
RU2647727C2
(HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS 2012
  • Ortega-Munos Alberto
  • Fajf Mattyu Kolin Tor
  • Martinell-Pedemonte Mark
  • Estyarte-Martines Mariya-De-Los-Ankheles
  • Valls-Vidal Nuriya
  • Kurts Guido
  • Kastro-Palomino-Lariya Khulio-Sesar
RU2681211C2

RU 2 539 574 C2

Authors

Shtajnkhagen Khenning

Shajper Bodo

Matter Khans

Makkort Gari

Bezhi Gijom

Gobervill' Paskal'

T'Er Beranzher

Dates

2015-01-20Published

2010-07-23Filed