MOTILIN-LIKE PEPTIDE COMPOUND HAVING IMPARTED TRANSMUCOSAL ABSORBING ABILITY Russian patent published in 2015 - IPC C07K14/63 A61K38/00 A61P1/00 

Abstract RU 2540012 C2

FIELD: biotechnologies.

SUBSTANCE: polypeptide has a sequence represented by the formula below X1 Va1 X2 Ile Phe Thr Tyr Gly X3 Leu Gln Arg X4 Gln Glu Lys Glu Arg X5 Lys Pro Gln (formula I). Links between amino acids, apart from X1-Val link, are amide links. The X1-Val link is an amide link or a link represented by the formula below 2

X1 is an aromatic amino acid or a heteroaromatic amino acid, X2 represents proline or sarcosine, X3 is glutaminic acid or asparaginic acid, X4 is methionine or leucine, X5 is asparagine or proline. The proposed invention may be used in medicine for treatment of a disease related to disturbed function of gastrointestinal tract.

EFFECT: invention makes it possible to efficiently treat diseases related to disturbed function of gastrointestinal tract.

7 cl, 5 dwg, 4 tbl, 5 ex

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Authors

Sato Sejdzi

Khanada Takesi

Vakabajasi Naomi

Masuda Jutaka

Kharada Juriko

Dates

2015-01-27Published

2010-07-29Filed