ISOLATED POLYNUCLEOTIDE, CODING POLIPEPTIDE, INVOLVED IN PYRIPYROPENE A BIOSYNTHESIS, VECTOR AND HOST CELL, CONTAINING THEREOF AND METHOD OF OBTAINING PYRIPYROPENE A PRECURSOR (VERSIONS) Russian patent published in 2015 - IPC C12N15/55 C12N15/63 C12N15/70 C12N15/80 C12P1/02 C12P1/04 A01P7/04 

FIELD: chemistry.

SUBSTANCE: claimed inventions deal with an isolated polynucleotide, coding a polypeptide, involved in biosynthesis of pyripyropene A, a vector and a host cell, including such a polypeptide, and methods of obtaining pyripyropene A precursors, including the host cell cultivation. The claimed polynucleotide codes the polypeptide, possessing any one or more of the activities - polyketide synthase, prenyltransferase, hydroxylase, acetyltransferase or adenylate synthase.

EFFECT: claimed inventions make it possible to synthesise pyripyropene A, which is an insecticidal agent, and can be used in the formation of plant resistance to pest insects.

16 cl, 11 dwg, 1 tbl, 11 ex