FIELD: biotechnology, biochemistry, microbiology, molecular biology.
SUBSTANCE: invention relates to polynucleotides that are able to accelerate biosynthesis of plavastatin precursor ML-236B in microorganisms producing ML-236B after their administration in these microorganisms. These polynucleotides are inserted in vectors that are used for transformation of microorganism-producers of pravastatin precursor that is an inhibitor of enzyme HMG-CoA-redcutase.
EFFECT: valuable biochemical properties of polynucleotides.
13 tbl, 6 dwg, 13 ex
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